Abstract: This paper chooses 1033 residents with different jobs of two districts in Zhengzhou city as the investigation objects,and it uses questionnaire investigation,data statistics and other methods to do the health investigation.The investigation results show that the proportion of district residents with different jobs who need the treatment and prevention of disease,self-care and science fitness knowledge is the highest.The result reflects district different people groups have different goals of keeping health.It also shows that in order to meet requirement of district people with different jobs,the knowledge of treatment and prevention of disease,physical health care should be often educated and the science fitness of district residents with different jobs should be often guided.