Abstract: Aiming at the present status of the traditional teaching mode, the unquantitative vocational skill assessment process, utilizing inside and outside school practicing bases not very well of higher vocational college secretary specialty, adopting the clear cultivation target, arranging practice teaching content properly, increasing practice teaching curriculum in good time, adopting various practice modes, developing practice teaching material with enterprises, establishing effective practice teaching management system, from cultivating double-qualified structure teacher team, playing a college-enterprise practice base role, creating a better inside school practice environment, constructing secretary specialty practice examination system, this paper establishes secretary specialty practice teaching guarantee system to construct practice teaching system which can highlight secretary specialty students’ advantages, and to make the vocational quality and vocational capability into job skills, then to cultivate the high-quality and high-skilled secretary talent to meet the society’s need.