Abstract: With the removal test research of self-regulating sodium ferrate to anionic synthetic detergent in domestic sewage, by the international standard Methylene Blue Spectrophotometric method, we find out that: Sodium ferrate has a better removal effect on anionic synthetic detergent in domestic sewage, if we add 10m l concentration of sodium ferrate is 1.41 g/L into per 100 ml of domestic sewage, we can make the removal rate of anion synthetic detergent in the samples reach 69.28%.