Abstract: Facing the current background of industry-education deep integration and the new requirements under the new normal of reform and development,higher vocational colleges must further deepen the innovation and reform of school-enterprise cooperation and talent cultivation mode,and explore the way of cultivating high-quality composite technical skilled talent to meet the needs of economic and social development.Based on the analysis of the problems existing in the process of school-enterprise cooperation in building industrial colleges,A school-enterprise deep cooperation education mode based on industry-education integration is explored,a new paradigm of school-enterprise cooperation in building co-construction of college campus,co-constitute of teachers,joint-progress of scientific research,joint-cultivation of talents and co-occurrence internationalization is proposed.